CD24 is a GPI-linked membrane sialoglycoprotein that is expressed on pro-B,pre-B and mature B cells, and its expression is decreased after B cell activation.CD24 is also found on granulocytes and a small fraction of thymocytes and neuroblastomas, but not on plasma cells.
CD24 may play a role in the regulation of B cell proliferation and differentiation.
CD24 is expressed in hematological malignancies as well as in a large variety of solid tumors.
A shift from apical localization to cytoplasmic staining of CD24 is a surrogate marker of stromal invasion in ovarian serous tumors of borderline malignancy.
CD24 protein can be a B cell differentiation marker that is expressed on mature resting B cells and disappears upon stimulation.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 500-1000 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of CD24. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to the N-terminal of Human CD24.
