84-2309-83　［取扱停止］CCL22 (ABCD 1, ABCD1, C C Motif Chemokine 22, CC Chemokine STCP 1, CC Chemokine STCP-1, ccl 22, Ccl22, CCL22_HUMAN, Chemokine (C C Motif) Ligand 22, DC/B CK, DCBCK, Macrophage-derived Chemokine, MDC(1-69), MDC(7-69), MGC34554, SCYA22, Small inducible cytokine Subfamily A (Cys Cys) Member 22, Small-inducible cytokine A22, STCP 1, STCP1, Stimulated T Cell chemotacti ...　221429

特徴

• Chemokines have been implicated in the regulation of stem/progenitor cell proliferation and movement.
• The C-C chemokines TARC (for thymus and activation-regulated chemokine, also designated small inducible cytokine A17) and MDC (for macrophage-derived chemokine, also designated small inducible cytokine A22 or STCP-1, for stimulated T cell chemotactic protein 1), are expressed in the thymus and spleen.
• C-C chemokine receptor CCR4, expressed by T helper type 2 polarized cells, is a high affinity receptor for both TARC and MDC.
• TARC is important in the recognition of skin vasculature by circulating T cells and in directing lymphocytes that are involved in systemic as opposed to intestinal immunity to its target tissues.
• MDC is involved in chronic inflammation and dendritic cell and lymphocyte homing.
• MDC and TARC lack suppressive activity against immature subsets of myeloid progenitors, which have been stimulated to proliferate by multiple growth factors.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.