Catalase is a peroxisome specific marker protein belonging to the catalase family.
Defects in the gene encoding for the catalase protein, CAT, can cause acatalasia, a disease characterized by the absence of catalase activity in red cells and associated with ulcerating oral lesions.
Catalase is also an important regulator of oxidative stress and inflammation, and may contribute to the development of rheumatoid arthritis.
Catalase, which can form a homotetramer, is found in nearly all aerobically respiring organisms and functions in protecting cells from the toxic effects of hydrogen peroxide.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of Catalase. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 341-390 of Human Catalase.
