This gene encodes a calcium/calmodulin-dependent serine protein kinase.
The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member.
These proteins are scaffold proteins and the encoded protein is located at synapses in the brain.
Mutations in this gene are associated with FG syndrome 4, mental retardation and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation.
Multiple transcript variants encoding different isoforms have been found for this gene.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of CASK. Species Crossreactivity: Human, mouse, rat
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Recombinant full length Human CASK.
Shelf Life:1year
Swiss Prot Number:O14936
EU Commodity Code:30021010
商品名:CASK (CAGH39, Caki, Calcium/calmodulin Dependent Serine Protein Kinase, Calcium/calmodulin Dependent Serine Protein Kinase (MAGUK Family), Calcium/calmodulin Dependent Serine Protein Kinase Membrane Associated guanylate Kinase, Calcium/calmodulin-Dependent Serine Protein Kinase, CAMGUK, CAMGUK Protein, CAMGUK, drosophila, Homolog of, casK, CMG, CSKP_HUMAN, DXPri1, DXRib1, FGS4, FLJ22219, FLJ31914, hCASK, LIN 2, Lin 2 Homolog, LIN2, Lin2 Homolog, MICPCH, MRXSNA, Pals3, Peripheral plasma Membrane Protein CASK, Protein lin-2 Homolog, TNRC8, Trinucleotide Repeat Containing 8, Vertebtate LIN2 Homolog,) 50ul