The MAGUK family includes several mammalian proteins, such as postsynaptic proteins, GKAPs, the tight junction associated proteins (ZO-1-3), and the caspase-associated recruitment domain (CARD) proteins, all of which are related to the Drosophila tumor suppressor discs-large (dlg) gene product.
CARD 8, also designated DACAR, NDPP1, TUCAN or CARDINAL, is a 431 amino acid protein that is expressed in the lung, ovary, testis, and placenta.
It regulates cellular responses controlled by NF-˚ B activation and may play a key role in apoptosis and chronic inflammatory disorders.
CARD 8 binds to caspase-1 and negatively regulates its activity.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of CARD8. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant full length Human CARD8.
Shelf Life：1year
Swiss Prot Number：Q9Y2G2
EU Commodity Code：30021010
商品名：CARD8 (Apoptotic Protein NDPP 1, Apoptotic Protein NDPP1, CARD 8, CARD Inhibitor of NF kappa B Activating Ligand, CARD Inhibitor of NF kappaB Activating Ligand, CARD Inhibitor of NF kappaB Activating Ligands, CARD-Inhibitor of NF-kappa-B-Activating Ligand, CARD8, CARD8, CARDINAL, Caspase Recruitment Domain Containing Protein 8, Caspase Recruitment Domain Family Member 8, Caspase Recruitment Domain Protein 8, Caspase Recruitment Domain-Containing Protein 8, DACAR, DKFZp779L0366, KI) 50ul
