CANT1 (calcium activated nucleotidase 1), also known as apyrase homolog, DBQD, SCAN1 (soluble calcium-activated nucleotidase 1) or SHAPY, is a 401 amino acid single-pass type II membrane protein of the endoplasmic reticulum and Golgi apparatus.
A member of the apyrase family, CANT1 functions as a calcium-dependent nucleotidase that preferentially binds UDP.
CANT1 is expressed at highest levels in testis, placenta, prostate and small intestine, and undergoes post-translational N-glycosylation and alternative splicing events to produce two isoforms.
Homozygous mutation in the gene encoding CANT1 is the cause of Desbuquois dysplasia, an autosomal recessive chondrodysplasia in which extreme prenatal and postnatal growth retardation is observed.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of CANT1. Species Crossreactivity: Human
