Voltage-dependent calcium channels are essential for the release of neurotransmitters.
Cacna2d1 (calcium channel, voltage-dependent, alpha2/delta subunit 1), also known as CACNA2, CCHL2A, MHS3 or CACNL2A, is a 1,091 amino acid single-pass type I membrane protein that contains one VWFA domain and one cache domain.
Expressed in skeletal muscle, aorta tissues and in the central nervous system (CNS), Cacna2d1 functions as an alpha2/delta subunit of voltagedependent calcium channels and plays an important role in calcium current density, as well as in excitation-contraction coupling.
The Cacna2d1 precursor is proteolytically processed to produce two functional subunits, designated alpha2-1 and delta1, which are disulfide-linked to one another.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of Cacna2d1. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 100-150 of Human Cacna2d1.
