84-2303-85 ［取扱停止］BTRC (Beta transducin Repeat Containing E3 Ubiquitin Protein Ligase, beta TrCP1, beta-transducin Repeat Containing, BETA-TRCP, betaTrCP, BTRC, bTrCP, bTrCP1, E3RSIkappaB, F box and WD Repeat Protein 1B, F box and WD Repeats Protein beta TrCP, F-box and WD Repeats Protein beta-TrCP, F-box/WD Repeat Protein 1A, F-box/WD Repeat-Containing Protein 1A, FBW1A, FBW1A, FB ... 221125
84-2303-85 ［取扱停止］BTRC (Beta transducin Repeat Containing E3 Ubiquitin Protein Ligase, beta TrCP1, beta-transducin Repeat Containing, BETA-TRCP, betaTrCP, BTRC, bTrCP, bTrCP1, E3RSIkappaB, F box and WD Repeat Protein 1B, F box and WD Repeats Protein beta TrCP, F-box and WD Repeats Protein beta-TrCP, F-box/WD Repeat Protein 1A, F-box/WD Repeat-Containing Protein 1A, FBW1A, FBW1A, FB ... 221125
ß-TrCP (beta-tranducin repeats containing protein), also designated E3RSIkB or FWD1, and HOS (homologous to Slimb) are F-box proteins that function as substrate recognition subunits of ubiquitin ligases.
HOS and ß-TrCP differ in their amino terminal regions, but exhibit high homology within the F-box and WD40 repeat-containing regions.
ß-TrCP mediates ubiquitin/proteasome-dependent degradation of CD4 and ubiquitination of various proteins including IkB and ß-catenin.
HOS has also been shown to regulate the degradation of IkB and ß-catenin in a similar manner.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of BTRC. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant full length Human BTRC.
Shelf Life：1year
Swiss Prot Number：Q9Y297
EU Commodity Code：30021010
商品名：BTRC (Beta transducin Repeat Containing E3 Ubiquitin Protein Ligase, beta TrCP1, beta-transducin Repeat Containing, BETA-TRCP, betaTrCP, BTRC, bTrCP, bTrCP1, E3RSIkappaB, F box and WD Repeat Protein 1B, F box and WD Repeats Protein beta TrCP, F-box and WD Repeats Protein beta-TrCP, F-box/WD Repeat Protein 1A, F-box/WD Repeat-Containing Protein 1A, FBW1A, FBW1A, FBXW1, FBXW1A, FWD1, HOS, mKIAA4123, pIkappaBalpha-E3 Receptor Subunit, Slimb) 50ul
