This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein.
The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6.
During hematopoietic cell differentiation, this gene is down-regulated.
It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression.
Multiple transcript variants encoding several different isoforms have been found for this gene.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of BCL11A. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant full length Human BCL11A.
Shelf Life：1year
Swiss Prot Number：Q9H165
EU Commodity Code：30021010
商品名：BCL11A (2810047E18Rik, B Cell CLL/lymphoma 11A (zinc Finger Protein), B Cell CLL/lymphoma 11A (zinc Finger Protein) Isoform 2, B Cell CLL/lymphoma 11A, B Cell lymphoma/leukaemia 11A, B-Cell CLL/lymphoma 11A, B-Cell lymphoma/Leukemia 11A, BC11A_HUMAN, BCL 11A, BCL-11A, BCL11A, BCL11A B Cell CLL/lymphoma 11A (zinc Finger Protein) Isoform 1, BCL11A L, BCL11A S, BCL11A XL, BCL11AL, BCL11AS, BCL11AXL, C2H2 Type zinc Finger Protein, COUP TF interacting Protein 1, COUP-TF-interacting Protein 1, Ctip 1, CTIP1, D930021L15Rik, Ecotropic Viral integration site 9, Ecotropic Viral integration site 9 Homolog, Ecotropic Viral integration site 9 Protein, Ecotropic Viral integration site 9 Protein Homolog, Evi 9, EVI-9, Evi9, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, mKIAA1809, OTTHUMP00000159788, OTTHUMP00000159789, OTTHUMP00000201250, OTTHUMP00000202084, Zinc Finger Protein 856, ZNF856,) 50ul
