84-2302-03　［取扱停止］Bcl-7a (B Cell CLL/lymphoma 7, B Cell CLL/lymphoma 7 Protein Family Member A, B Cell CLL/lymphoma 7A, B-Cell CLL/lymphoma 7 Protein Family Member A, BCL 7, BCL7, bcl7a, BCL7A) 100ul　221026

特徴

• Bcl-7a (B-cell CLL/lymphoma 7 protein family member A) is a 210 amino acid protein that belongs to the Bcl-7 family.
• Chromosomal aberrations involving a disruption of the amino-terminus of Bcl-7a may be a cause of B-cell nonHodgkin lymphoma (BNHL).
• Bcl-7b and Bcl-7c proteins share 90% identity with the N-terminal 51 amino acids of Bcl-7a, suggesting that the three genes are members of an evolutionarily conserved gene family.
• Bcl-7 gene family may be involved in early development.
• The Bcl-7a protein interacts with a novel human Polycomb ring finger gene and exists as two alternatively spliced isoforms.
• Bcl-7a may play a role in GC reaction and/or B-cell lymphomagenesis.
• The Bcl-7a gene maps to human chromosome 12q24.31.
• Chromosome 12 encodes over 1,100 genes and comprises ~4.5% of the human genome.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.