BAP29 (BCR-associated protein 29), also known as BCAP29 (B-cell receptor-associated protein 29), is a multi-pass membrane protein localizing to the endoplasmic reticulum (ER) and belonging to the BCAP29/BCAP31 family of proteins.
It is ubiquitously expressed with predominant expression in brain and testis.
BAP29 contains a hydrophobic N-terminus, three transmembrane domains, a coiled-coil region and a C-terminal double-lysine motif that is implicated in vesicular transport.
BAP29 exists as a homodimer or as a heterodimer with BAP31 and plays a role in membrane IgD molecule retention in the ER.
In addition, the BAP29/BAP31 complex functions as a cargo receptor for MHC class I molecules and is important for recruiting the class I molecules to exit sites of the ER.
The BAP29/BAP31 complex is also essential for proper trafficking from the ER to the Golgi.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of BCAP29. Species Crossreactivity: Human
