ZAG (Zn-a2-glycoprotein, also designated Zn-a2-gp) is a soluble, secreted protein found in serum and other body fluids (such as cerebrospinal fluid, blood plasma, urine and sweat).
ZAG has a tendency to precipitate with zinc salts, has electrophoretic mobility in the region of the two globulins, and has 18% carbohydrate content.
A member of the immunoglobulin superfamily, ZAG has a high degree of sequence similarity to class-I major histocompatibility complex (MHC) antigens.
The ZAG structure includes a large groove analogous to class I MHC peptide binding grooves.
The crystal structure of ZAG resembles a class I MHC heavy chain but does not bind the class I light chain b-2-Microglobulin, unlike other MHC related proteins.
ZAG stimulates lipid degradation in adipocytes and its overexpression causes the extensive fat losses associated with some advanced cancers.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of AZGP1. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to residues in Human AZGP1.
