Arylsulfatase E, also known as CDPX, CDPX1 or CDPXR, is a 589 amino acid Golgi apparatus protein expressed in the pancreas, liver and kidney.
Belonging to the sulfatase family, Arylsulfatase E may be essential for the correct composition of cartilage and bone matrix during development.
Inhibited by warfarin, Arylsulfatase E activity occurs under optimal pH and temperature.
Defects in the gene encoding Arylsulfatase E are the cause of chondrodysplasia punctata X-linked recessive type 1 (CDPX1), which is characterized by aberrant bone mineralization, severe underdevelopment of nasal cartilage and distal phalangeal hypoplasia.
Arylsulfatase E has no activity toward steroid sulfates.
Applications:Suitable for use in Western Blot, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunocytochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of ARSE. Species Crossreactivity: Human
Isotype：IgG
Calc Applications Abbrev：IC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to amino acids 208-253 of Human ARSE.
