84-2297-99　［取扱停止］AR-beta3 (Beta-3 Adrenergic Receptor, Beta-3 adrenoReceptor, Beta-3 adrenoceptor, ADRB3, ADRB3R, B3AR, AR beta3, ARbeta3, beta3-AR, beta3 AR, beta3AR) 50ul　220823

特徴

• Beta 3-adrenergic receptors (b3-ARs) bind cathecholamines (epinephrine, norepinephrine), and primarily regulate lipolysis and thermogenesis in adipose.
• b3-ARs are present in adipose tissues, heart, and in smooth muscle of bladder, colon, small intestine, and stomach.
• The human corpus cavernosum exhibits basal b3-AR-mediated vasorelaxant tone and activity is linked to inhibition of the RhoA/Rho-kinase pathway.
• b3-AR interacts directly with the SH3 domain of Src through proline-rich motifs (PXXP) in the third intracellular loop and the carboxy-terminus.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.