84-2296-83　［取扱停止］AP2M1 (AP-2 Complex Subunit mu, AP-2 mu Chain, Adapter-Related Protein Complex 2 Subunit mu, Adaptin-mu2, Adaptor Protein Complex AP-2 Subunit mu, Clathrin assembly Protein Complex 2 mu medium Chain, Clathrin coat assembly Protein AP50, Clathrin coat-Associated Protein AP50, HA2 50kD Subunit, Plasma Membrane adaptor AP-2 50kD Protein, AP2M1, CLAPM1, KIAA0109, AP-2 ...　220765

特徴

• Adaptins are heterotetrameric subunits of adaptors, which are complexes involved in the formation of Clathrin-coated pits for vesicle-mediated endocytosis.
• Clathrin and its associated heterotetrameric protein complexes make up the main protein components of the coat surrounding the cytoplasmic face of coated vesicles.
• The Adaptin family, comprising a, b, b' and g classes, is also responsible for the transport of ligand-receptor complexes from plasma membranes and the trans-Golgi network to lysosomes.
• Two main types of adaptor proteins (APs), AP-1 and AP-2, are found in Clathrin-coated structures located at the Golgi complex and the plasma membrane of mammalian cells, respectively.
• Adaptor protein complex 2 (AP-2) is composed of two large Adaptins (a1A/AP2A1 and b1/AP2B1), a medium Adaptin (m2/AP-2m1) and a small Adaptin (s2 long/AP2S1).
• AP-2m1, a 435 amino acid protein, links Clathrin to receptors in coated vesicles.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.