84-2296-69　［取扱停止］ANXA4 (Annexin A4, 35-beta calcimedin, Annexin IV, Annexin-4, Carbohydrate-Binding Protein p33/p41, Chromobindin-4, Endonexin I, Lipocortin IV, P32.5, PP4-X, Placental anticoagulant Protein II, PAP-II, Protein II, ANXA4, ANX4) 100ul　220758

特徴

• The annexin family of calcium-binding proteins is composed of at least ten mammalian genes.
• It is characterized by a conserved core domain which binds to phospholipids in a Ca++-dependent manner and a unique amino terminal region which may confer binding specificity .
• Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion.
• For example, the crystal structure of Annexin III has suggested a hydrophilic amino terminus with possible Ca++ channel activity .
• Similarly, Annexin V has ion channel properties.
• Annexin IV, also referred to as endonexin, functions to regulate Cl- flux by mediating calmodulin kinase II (CaMKII) activity and Annexin V has been shown to regulate PKC activity.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.