84-2296-52　［取扱停止］Annexin 5 (Anchorin CII antibodyAnnexin 5 antibodyAnnexin A5 antibodyAnnexin V antibodyAnnexin-5 antibodyAnnexin5 antibodyAnnexinA5 antibodyAnnexinV antibodyANX 5 antibodyANX A5 antibodyANX5 antibodyANXA5 antibodyANXA5 antibodyCalphobindin I antibodyCBP I antibodyCBP-I antibodyEndonexin II antibodyENX 2 antibodyENX2 antibodyLipocortin V antibodyPAP I antibodyPAP-I ...　220749

特徴

• Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion.
• For example, the crystal structure of Annexin III has suggested a hydrophilic amino-terminus with possible Ca2+ channel activity.
• Similarly, Annexin V has ion channel properties.
• Annexin IV, also referred to as endonexin, functions to regulate Cl-flux by mediating calmodulin kinase II (CaMKII) activity and Annexin V has been shown to regulate PKC activity.
• Annexin V is ubiquitously expressed at high levels in tissues and cells grown in tissue culture, while Annexin VIII exhibits a more limited distribution.
• Where co-expressed in the same tissues, Annexin VIII is often expressed at a 100-fold lower level than Annexin V.
• However, Annexin VIII is preferentially expressed in acute promyelocytic leukemia (APL) cells, which may relate to its role in hematopoietic cell differentiation.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.