The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing.
The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor.
The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells.
This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells.
Multiple transcript variants encoding different isoforms have been found for this gene.
A pseudogene has been identified on chromosome 20.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of AIMP1. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant full length Human AIMP1.
Shelf Life：1year
Swiss Prot Number：Q12904
EU Commodity Code：30021010
商品名：AIMP1 (AIMP 1, AIMP1, AIMP1/p43, AIMP1_HUMAN, Aminoacyl tRNA Synthetase Complex-interacting multifunctional Protein 1, ARS interacting multifunctional Protein 1, EMAP 2, EMAP-2, EMAP-II, EMAP2, EMAPII, Endothelial monocyte Activating Polypeptide 2, Endothelial monocyte Activating Polypeptide, Endothelial monocyte-Activating Polypeptide 2, Endothelial monocyte-Activating Polypeptide II, HLD3, Multisynthase Complex auxiliary Component p43, MultiSynthetase Complex auxiliary Component p43, OTTHUMP00000219673, p43, Scye 1, Scye1, Scye1, formerly, Small inducible cytokine Subfamily E Member 1, Small inducible cytokine Subfamily E, Member 1 (Endothelial monocyte-Activating), Small inducible cytokine Subfamily E, Member 1, formerly,) 100ul
