84-2293-79　ADM (Adrenomedullin, Proadrenomedullin N-20 Terminal peptide, ProAM N-Terminal 20 peptide, PAMP, ProAM-N20, ADM, AM) 50ul　220609

特徴

• Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity.
• ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintenance of cardiovascular functioning.
• In hypertensive patients, the level of ADM in plasma is upregulated.
• Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage.
• ADM has strong natriuretic actions.
• ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption.
• ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion.
• Applications:Suitable for use in Immunohistochemistry.
• Other applications not tested.
• Recommended Dilutions:Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.