84-2293-69　［取扱停止］ADH4 (ADH 4, ADH-1, ADH-2, ADH2, Adh4, ADH4_HUMAN, Alcohol Dehydrogenase 4 (class II) pi Polypeptide, Alcohol Dehydrogenase 4, Alcohol Dehydrogenase class II pi Chain, Alcohol Dehydrogenase pi Isozyme ADH class II, Aldehyde Reductase, Class II alcohol Dehydrogenase 4 pi Subunit) 50ul　220604

特徴

• ADH4 (alcohol dehydrogenase 4) is a 380 amino acid protein that belongs to the zinc-containing alcohol dehydrogenase family of enzymes that function to metabolize a wide variety of substrates, including retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products.
• Localized to the cytoplasm and existing as a homodimer, ADH4 uses zinc as a cofactor to catalyze the NAD+-dependent conversion of an alcohol to an aldehyde or a ketone, thereby participating in the metabolic degradation of alcohols within the body.
• Multiple isoforms of ADH4 exist due to alternative splicing events.
• The gene encoding ADH4 maps to a cluster of alcohol dehydrogenase genes on human chromosome 4, a chromosome that encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.