Tenr (testis nuclear RNA-binding protein), also known as ADAD1 (adenosine deaminase domain containing 1), is a 576 amino acid nuclear protein that plays a role in spermatogenesis and belongs to the ADAD family.
Existing as three alternatively spliced isoforms, Tenr contains one A to I editase domain and a DRBM (double-stranded RNA-binding) domain.
The gene encoding Tenr maps to human chromosome 4, which represents ~6% of the human genome and contains nearly 900 genes.
Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4.
FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer.
Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human ADAD1. Species Crossreactivity: mouse and rat.
