84-2292-15　［取扱停止］ABO (A Transferase, Abo, ABO blood group (Transferase A alpha 1-3 N acetylgalactosaminylTransferase Transferase B alpha 1 3 galactosylTransferase), ABO glycosylTransferase, B (A) alpha 1, 3 glactosylTransferase, B Transferase, BGAT, Fucosylglycoprotein 3 alpha galactosylTransferase, Fucosylglycoprotein 3-alpha-galactosylTransferase, Fucosylglycoprotein alpha N ace ...　220526

特徴

• Histo-blood group ABO system transferase (NAGAT) is a member of the glycosyltransferase 6 family of proteins and the basis of the ABO blood group system.
• The histo-blood group ABO involves three carbohydrate antigens: A, B and H; the NAGAT protein functions as the basis of this group.
• A, B and AB individuals express a glycosyltransferase activity converting the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), while O individuals do not express this glycosyltransferase activity.
• The B phenotype of NAGAT differs from the A form by a few residue substitutions, whereas the O form is a result of a single base frame-shift deletion in the N-terminal extremity of the gene.
• The NAGAT protein localizes to the Golgi apparatus and its conserved DXD motif functions in cofactor binding.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.