84-2291-76 [取扱停止]ABCG1 (ATP-Binding Cassette sub-Family G Member 1, ATP-Binding Cassette Transporter 8, White Protein Homolog, ABC8, WHT1) 100ul 220507
84-2291-76 [取扱停止]ABCG1 (ATP-Binding Cassette sub-Family G Member 1, ATP-Binding Cassette Transporter 8, White Protein Homolog, ABC8, WHT1) 100ul 220507
ABCG1 (also designated ABC8 or human white gene), a member of the evolutionary conserved family of ATP-binding cassette (ABC) transporters, exhibits high homology with the Drosophila white gene.
ABC transporters couple the energy of ATP hydrolysis to the translocation of various molecules across biological membranes.
These proteins contain characteristic ATP-binding domains and transmembrane domains which form a channel-like structure for transport.
ABCG1 functions to regulate cholesterol and phospholipid transport in macrophages.
ABCG1 is highly expressed in several tissues, including brain, spleen, lung and placenta, and has been localized to the cell surface and intracellular compartments of cholesterol-laden macrophages.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity:Recognizes endogenous levels of ABCG1. Species Crossreactivity: Human, mouse, rat
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to amino acids 633-678 of Human ABCG1.