84-2291-65　［取扱停止］ABCC5 (ABC 33, ABC33, ABCC 5, ABCC5, ATP Binding Cassette sub Family C (CFTR/MRP) Member 5, ATP Binding Cassette sub Family C Member 5, ATP-Binding Cassette sub-Family C Member 5, Canalicular Multispecific Organic Anion Transporter C, DKFZp686C1782, EST277145, MOAT C, MOAT-C, MOATC, MRP 5, MRP5_HUMAN, Multi specific Organic Anion tranporter C, Multi-specific Organ ...　220502

特徴

• The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.
• ABC proteins transport various molecules across extra- and intra-cellular membranes.
• ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
• This protein is a member of the MRP subfamily which is involved in multi-drug resistance.
• This protein functions in the cellular export of its substrate, cyclic nucleotides.
• This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides.
• Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.