The ATP-binding cassette (ABC) superfamily is comprised of transmembrane proteins involved in energy-dependent transport of a variety of substrates across membranes.
ABCA6 is a 1,617 amino acid protein belonging to the ABC transporter family.
ABCA6 is up-regulated during monocyte differentiation into macrophages, suggesting a role in macrophage lipid homeostasis.
ABCA6 contains two ABC transporter domains and is expressed as three isoforms produced by alternative splicing.
ABCA6 is present at highest levels in adult liver, with significant levels found in many adult tissues and fetal lung, kidney and liver.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of ABCA6. Species Crossreactivity: Human, mouse, rat
