A1BG (alpha-1B-glycoprotein), also known as A1B, ABG, GAB or HYST2477, is a 495 amino acid secreted glycoprotein that contains five immunoglobulin (Ig)-like V-type domains and belongs to the immunoglobulin superfamily.
At an average concentration of 22mg/dl, A1BG is expressed in normal adult plasma and is thought to be involved in the regulation of cell behavior and cell recognition.
In plasma, A1BG specifically binds to human CRISP-3, a member of the cysteine-rich secretory protein (CRISP) family comprised of evolutionarily conserved proteins which are believed to play a role in the innate immune system.
Through its association with CRISP-3, A1BG is believed to function in protecting the body from the circulation of free CRISP-3, a circumstance with potentially harmful effects.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of A1BG. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 182-227 of Human A1BG.
