Hepatitis C virus (HCV) represents the major etiologic agent of non-A, non-B hepatitis.
The pathological changes in hepatitis C are characterized by the histologic triad of lymphoid aggregates in portal tracts, epithelial damage of small bile ducts, and micro-and macro-vesicular steatosis.
HCV antigens are visible in the cytoplasm of infected hepatocytes by immunohistochemical staining with mono-or polyclonal antibodies.
These studies are important to determine the viral load and expression pattern of HCV in the infected liver.
The mechanism of hepatocyte and bile duct injury in HCV infection appears to be related to the host immune response to the virus.
Direct viral cytopathogenicity may also play a role.(1)
Applications:Suitable for use in ELISA and Western Blot.
Other applications have not been tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C before opening.
DO NOT FREEZE! Stable at 4°C as an undiluted liquid.
Dilute only prior to immediate use.
Stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
Freezing alkaline phosphatase conjugates will result in a substantial loss of activity.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：goat
Grade：Highly Purified
Purity：Purified IgG fraction to a purity of >95%.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. No stabilizing proteins added. Labeled with Alkaline Phosphatase (AP).
Specificity：Recognizes the Hepatitis C Virus Core antigen aa1-120.
