At least 9 distinct polymorphic forms of apolipoproteins are known.
The apolipoproteins act as stabilizers of the intact lipoprotein particles.
Quantitative measurements of HDL, LDL and VLDL particles in human serum are often used to estimate an individuals' relative risk of coronary heart disease.
In addition, quantitative immunological measurements of certain apolipoproteins (especially A1 and B) have been suggested to be more accurate estimators of coronary heart disease than measurements of lipoprotein particles (especially HDL and LDL).
Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein.
It inhibits lipoprotein lipase and hepatic lipase and it is thought to delay catabolism of triglyceride-rich particles.
An increase in apoC-III levels induces the development of hypertriglyceridemia.
Applications:Suitable for use in ELISA, Western Blot, Enzyme Conjugation, or Biotinylation.
Other applications not tested.
Recommended Dilution:ELISA: 1:200-1:40,000Western Blot: 1:200-1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C before opening.
DO NOT FREEZE! Stable at 4°C as an undiluted liquid.
Dilute only prior to immediate use.
Stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
Freezing alkaline phosphatase conjugates will result in a substantial loss of activity.
Note: Applications are based on unconjugated antibody.
仕様
Size:100ul
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. No stabilizing proteins added. Labeled with Alkaline Phosphatase (AP).
Specificity:Recognizes human Apolipoprotein CIII (Apo CIII).