The protein encoded by this gene is a member of the apolipoprotein C1 family.
This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages.
A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome.
This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster.
Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Apolipoprotein C-I appears to modulate the interaction of APOE with beta migrating VLDL and inhibit binding of beta VLDL to the LDL receptor related protein.
Applications:Suitable for use in ELISA, Western Blot, Enzyme Conjugation, or Biotinylation.
Other applications not tested.
Recommended Dilution:ELISA: 1:5,000-1:20,000Western Blot: 1:200-1:5,000 Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: PE conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. No stabilizing proteins added. Labeled with R-Phycoerythrin (PE).
Specificity：Recognizes human Apolipoprotein CI (Apo CI).
