It has recently been shown that SARS (severe acute respiratory syndrome) is caused by a human coronavirus.
Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans.
Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb).
The first step in coronavirus infection is binding of the viral spike protein, a 139-kD protein, to certain receptors on host cells.
The spike protein is the main surface antigen of the coronavirus.
The glycosilated spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients.
Applications:Suitable for use in ELISA.
Other applications have not been tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C.
For long-term storage, aliquot and store at 4°C.
Aliquots are stable at 4°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. No stabilizing proteins added. Labeled with Biotin.
Specificity：Recognizes the C-terminal of the spike protein of SARS-associated coronavirus.
Isotype：IgG
Calc Applications Abbrev：E
Immunogen：Synthetic peptide corresponding to amino acids at the C-terminus of the SARS Spike glycoprotein.
