The protein encoded by this gene is a member of the apolipoprotein C1 family.
This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages.
A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome.
This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster.
Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Apolipoprotein C-I appears to modulate the interaction of APOE with beta migrating VLDL and inhibit binding of beta VLDL to the LDL receptor related protein.
Applications:Suitable for use in ELISA, Western Blot, Enzyme Conjugation, or Biotinylation.
Other applications not tested.
Recommended Dilution:ELISA: 1:5,000-1:20,000Western Blot: 1:200-1:5,000 Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. No stabilizing proteins added. Labeled with Biotin.
Specificity：Recognizes human Apolipoprotein CI (Apo CI).
