Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA.
Novel influenza virus strains emerge periodically to which humans have little or no immunity, resulting in devastating pandemics.
Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found.
These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes.
During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong.
There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low.
Although it has been known that cleavage site and glycosylation patterns of the HA protein play important roles in determining the pathogenicity of H5 avian influenza viruses, it has only recently been shown that an additional glycosylation site within the globular head of the NA protein also contributes to the high virulence of the H5N1 virus.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilutions:ELISA: 1ug/ml Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C before opening.
DO NOT FREEZE! Stable at 4°C as an undiluted liquid.
Dilute only prior to immediate use.
Stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Further dilutions can be made in assay buffer.
Allophycocyanin (APC) is light sensitive.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide and a stabilizer. Labeled with Allophycocyanin (APC).
Specificity：Recognizes the hemagglutinin peptide from the swine-origin Influenza A/California/14/2009. Does not cross-react with the corresponding peptide from seasonal Influenza A/Brisbane/59/2007 (H1N1).
Isotype：IgG
Immunogen：Synthetic peptide corresponding to the hemagglutinin protein of the swine-origin Influenza A/California/14/2009 (H1N1) (ACQ76314)
