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84-2285-71 [取扱停止]CX3CR1 (NT) (Beta Chemokine Receptor-like 1, CCRL1, Chemokine C-X3-C Motif Receptor 1, CX3C Chemokine Receptor 1, C-X3-C CKR-1, CX3C CKR-1, CMK-BRL-1, CMKBLR1, CMKDR1, Fractalkine Receptor, GPR13, GPRV28, V28) (APC) 100ul C8300-01B-APC
84-2285-71 [取扱停止]CX3CR1 (NT) (Beta Chemokine Receptor-like 1, CCRL1, Chemokine C-X3-C Motif Receptor 1, CX3C Chemokine Receptor 1, C-X3-C CKR-1, CX3C CKR-1, CMK-BRL-1, CMKBLR1, CMKDR1, Fractalkine Receptor, GPR13, GPRV28, V28) (APC) 100ul C8300-01B-APC
特徴
- CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection.
- The genes encoding human, mouse, and rat CX3 CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively.
- The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1.
- Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine.
- CX3CR1 mediates leukocyte migration and adhesion.
- CX3CR1 is expressed in a variety of human tissues and cell lines.
- Applications:Suitable for use in Western Blot, Flow Cytometry (Not Tested), and Immunohistochemistry.
- Other applications have not been tested.
- Recommended Dilution:Immunohistochemistry: Paraffin sectionsOptimal dilutions to be determined by the researcher.
- Storage and Stability:Store product at 4°C in the dark.
- DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
- Dilute required amount only prior to immediate use.
- Further dilutions can be made in assay buffer.
- Caution: APC conjugates are sensitive to light.
- For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Note: Applications are based on unconjugated antibody.
仕様
- Size:100ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by Immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide and a stabilizer. Labeled with Allophycocyanin (APC).
- Specificity:Recognizes human CX3CR1, N-terminal. Species Crossreactivity: mouse, rat.
- Isotype:IgG
- Calc Applications Abbrev:IHC WB
- Calc Crossreactivity:Hu Mo Rt
- Immunogen:Synthetic peptide corresponding to aa2-21 of human CX3CR1. The sequence diffferes from mouse and rat CX3CR1 by 4aa.
- Shelf Life:1year
- EU Commodity Code:30021010
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
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