The protein encoded by this gene is a member of the apolipoprotein C1 family.
This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages.
A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome.
This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster.
Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Apolipoprotein C-I appears to modulate the interaction of APOE with beta migrating VLDL and inhibit binding of beta VLDL to the LDL receptor related protein.
Applications:Suitable for use in ELISA, Western Blot, Enzyme Conjugation, or Biotinylation.
Other applications not tested.
Recommended Dilution:ELISA: 1:5,000-1:20,000Western Blot: 1:200-1:5,000 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C before opening.
DO NOT FREEZE! Stable at 4°C as an undiluted liquid.
Dilute only prior to immediate use.
Stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Further dilutions can be made in assay buffer.
Allophycocyanin (APC) is light sensitive.
Note: Applications are based on unconjugated antibody.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide and a stabilizer. Labeled with Allophycocyanin (APC).
Specificity:Recognizes human Apolipoprotein CI (Apo CI).