84-2279-08 ［取扱停止］Oxoglutarate Dehydrogenase (OGDH, E1k, OGDC, AKGDH) 200ul 219117
特徴
- This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex.
- This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle.
- The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor.
- A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.
- Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Applications:Suitable for use in Western Blot, Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：200ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by affinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
- Specificity：Recognizes human OGDH. Species Crossreactivity: Mouse, rat
- Isotype：IgG
- Calc Applications Abbrev：IHC WB
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Recombinant protein corresponding to human OGDH.
- Shelf Life：1year
- Swiss Prot Number：Q02218
- EU Commodity Code：30021010
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