84-2276-89　［取扱停止］KCNH1 (Potassium Voltage-gated Channel Subfamily H Member 1, EAG, EAG1, h-eag, Kv10.1) 200ul　219039

特徴

• Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints.
• Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
• This gene encodes a member of the potassium channel, voltage-gated, subfamily H.
• This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel.
• It is activated at the onset of myoblast differentiation.
• The gene is highly expressed in brain and in myoblasts.
• Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation.
• Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.