The inositol (1,4,5)-trisphosphate receptor (InsP3R) regulates calcium release from storage within cells and plays an important role in neuronal function.
InsP3R has been linked to Huntington’s disease.
InsP3R has also been linked to the association between cAMP and Ca2+ signaling in regions of the brain, including the neostriatum.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:200-1:1000 using ECL on rat brain membranes.
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:200ul
Host:rabbit
Source Antibody:rat
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a lyophilized powder from PBS, pH 7.4, 1% BSA, 5% sucrose, 0.025% sodium azide. Reconstitute with 200ul of sterile deionized H20.
Specificity:Recognizes rat ITPR1. The epitope does not share homology with any other known proteins. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Mo Rt
Immunogen:Synthetic peptide corresponding to aa2732-2750 from rat ITPR1. Species sequence homology: human