The inositol (1,4,5)-trisphosphate receptor (InsP3R) regulates calcium release from storage within cells and plays an important role in neuronal function.
InsP3R has been linked to Huntington’s disease.
InsP3R has also been linked to the association between cAMP and Ca2+ signaling in regions of the brain, including the neostriatum.
Applications:Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:1500Optimal dilutions to be determined by the researcher.
Control:Rat brain microsomal tissue lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：rat
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
Specificity：Recognizes rat InsP3R at the cytoplasmic domain. Species Crossreactivity: human, mouse, porcine, primate and rhesus macaque.
Isotype：IgG
Calc Applications Abbrev：IHC IP WB
Calc Crossreactivity：Hu Mc Mo Po Rt
Immunogen：Linear peptide corresponding to the cytoplasmic domain of rat InsP3R, conjugated to KLH.
