Transduces a signal by increasing the intracellular calcium ions level.
Involved in haematopoiesis and in cardiac ventricular septum formation.
Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells.
Could be involved in cerebellar development.
In the CNS, could mediate hippocampal-neuron survival.
Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates.
Promotes Env-mediated fusion of the virus.
Applications:Suitable for use in Western Blot, Immunoprecipitation and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1-2ug/mlImmunocytochemistry: 10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity：Recognizes the N-terminal domain of CXCR4.
Isotype：IgG
Calc Applications Abbrev：IC IP WB
Calc Crossreactivity：Hu
Immunogen：Peptide corresponding to the N-terminal domain of human CXCR4.
