Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation.
Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus.
Specifically binds and stimulates the cGMP production of the NPR1 receptor.
Binds the clearance receptor NPR3.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Western Blot: 0.01-0.03ug/mlImmunohistochemistry(Paraffin): 5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes human NPPA. The immunizing peptide represents aa137-150 of the precursor NPPA. Species Crossreactivity: mouse, rat
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to RIGAQSGLGCNSFR from the C-terminus of human NPPA. Species sequence homology: Bovine, Chimpanzee, Canine, Gorilla, Hamster, Equine, Monkey, Orangutan, Rabbit, Sheep.
