The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS.
They have a role in both its formation and stabilization.
The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis.
Applications:Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:2000-1:5000Immunohistochemistry(Paraffin): 1:500Immunocytochemistry: 1:1000-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:chicken
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Specificity:Recognizes MBP gene product shared between the human (NP_002376, NCBI) and mouse (NP_034907, NCBI) sequences. Species Crossreactivity: Human, Mouse
Isotype:IgY
Calc Applications Abbrev:IC IHC WB
Calc Crossreactivity:Hu Mo
Immunogen:Recombinant protein corresponding to human Myelin Basic Protein conjugated to KLH.