Edg4 is a Lysophospholipid/Lysosphingolipid Receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA).
It enhances the transcription of serum response element (SRE) reporter genes.
In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion.
Applications:Suitable for use in Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry(Paraffin): 10-20ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human LPAR2. BLAST analysis of the peptide immunogen showed no homology with other Recognizes human proteins.
Isotype:IgG
Calc Applications Abbrev:IC IHC
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to 18aa from human LPAR2 at cytoplasmic domain of human LPAR2 / EDG4. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Panda, Bovine, Canine, Bat, Equine, Porcine (100%); Mouse, Elephant (94%); Rat (89%); Rabbit (83%).