Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility.
Acts in assocation with DOCK1 and CRK.
Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases.
May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 By similarity.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1-3ug/mlImmunohistochemistry(Paraffin): 5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes human ELMO3. Species Crossreactivity: Gibbon, Gorilla, Equine, Monkey, Porcine.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Eq Hu Mk Po
Immunogen：Synthetic peptide corresponding to TNFNFCYDCSIAEP from human ELMO3 at C-terminus (NP_078988.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Equine, Porcine (100%); Panda (93%); Mouse, Hamster, Bat, Rabbit (86%).
