DOPA decarboxylase (DDC) belongs to the group II decarboxylase family of proteins.
It is an important protein in the catecholamine biosynthesis pathway.
DDC catalyzes the second reaction in the biosynthesis of catecholamines, trace amines and serotonin.
It can form a homodimer and is expressed in the central nervous system.
DDC can be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease, neuroendocrine tumors and drug abuse.
Defects in DDC gene may cause the autosomal recessive disorder AADC deficiency.
Applications:Suitable for use in Immunofluorescence, ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1-2ug/mlImmunohistochemistry: paraffinOptimal dilutions to be determined by the researcher.
Positive Control:Human Lung Tissue Lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity：Recognizes human DOPA Decarboxylase. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IF IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Peptide corresponding to 14aa, located within aa390-440, near the carboxy terminal of human DOPA Decarboxylase. Species sequence homology: bovine, porcine and guinea pig
