Isoform 2 and isoform 3 may act as decoy receptors.
SUBUNIT: Associates with TRAF1, TRAF2, TRAF3 and TRAF5.
Contains 3 TNFR-Cys repeats.
Tissue Specificity: Highly expressed in adult brain, and in embryos from day 11-17, but not earlier.
Detected in embryonic brain and epithelium, and at lower levels in adult heart, lung and liver.
In neonatal mice, mainly in hair follicles and neuron-like cells in the cerebellum, but not in the skin epidermis.
Isoform 3 was found in embryonic day 17.5 skin but not in brain and liver.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:500-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Source Antibody：mouse
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder. Reconstitute with 100ul sterile ddH2O.
Specificity：Recognizes mouse TROY. Species Crossreactivity: Rat
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Mo Rt
Immunogen：Synthetic peptide corresponding to aa75-88, CRPHRF KEDWGFQK, from mouse TROY conjugated to Blue Carrier Protein. Cellular Localization: Isoform 1, isoform 3, isoform 4: Cell membrane; single-pass type I membrane protein (Probable). Isoform 2: Secreted protein (Probable).
