Tyrosine-protein phosphatase non-receptor type 11 (SHP2) plays a regulatory role in various cell signaling events such as mitogenic activation, metabolic control, transcription regulation and cell migration.
SHP2 is highly expressed in the cytoplasm of heart, brain and skeletal muscle tissue.
3 isoforms of SHP2 are produced by alternative splicing.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in 5mg BSA, 0.9mg sodium chloride, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg sodium azide. Reconstitute with 100ul sterile ddH2O.
Specificity：Recognizes human Tyrosine-protein Phosphatase Non-receptor Type 11. Predicted length of 597 residues and MW of 68kD.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Rt
Immunogen：Synthetic peptide corresponding to aa578-592, EDSARVYENVGLMQQ, from the C-terminal of human Tyrosine-protein Phosphatase Non-receptor Type 11, coupled to carrier protein BSA.
