84-2266-96 [取扱停止]NOGO-A (RTN 4A, Nogo-A, RTN-xL, Reticulon-4, Neurite Outgrowth Inhibitor, Foocen, NSP) 100ug 215405
特徴
Neurite Outgrowth Inhibitor (NOGO) is a myelin associated neurite growth inhibitor found in oligodendrocyte and central nervous system (CNS) myelin membranes of the adult CNS.
NOGO plays a role in blocking axonal regeneration in the CNS of higher vertebrates.
6 isoforms have been observed arising from alternative splicing.
NOGO-A (Isoform 1) is specifically expressed in brain and testes and weakly expressed in heart and skeletal muscle.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/mlImmunohistochemistry (formalin fixed/paraffin embedded tissues): 0.5-1ug/ml.
Heat mediated antigen retrieval is required.
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder in 5mg BSA, 0.9mg sodium chloride, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg sodium azide. Reconstitute with 100ul sterile ddH2O.
Specificity:Recognizes human NOGO-A. Species Crossreactivity: Mouse, rat
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to aa1170-1192 from the C-terminal of human NOGO-A.
Shelf Life:1year
Swiss Prot Number:Q9JK11
EU Commodity Code:38221010
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