Mitofusin 2 (MFN2) is an important transmembrane GTPase required for mitochondrial fusion.
MFN2 has a role in the regulation of vascular smooth muscle cell proliferation.
The protein is highly expressed in heart and skeletal muscle and ubiquitously expressed at low levels.
2 isoforms of MFN2 are produced by alternative splicing.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder in 5mg BSA, 0.9mg sodium chloride, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg sodium azide. Reconstitute with 100ul sterile ddH2O.
Specificity:Recognizes human Mitofusin 2. Species Crossreactivity: Rat. Predicted length of 757 residues and MW of 86kD.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Rt
Immunogen:Synthetic peptide corresponding to aa6-25 from the N-terminal of human Mitofusin 2, coupled to carrier protein BSA. Species Sequence Homology: Mouse