Glial Fibrillary Acidic Protein (GFAP) is a 50kD intra-cytoplasmic filamentous protein of the cytoskeleton in astrocytes.
During the development of the central nervous system, it is a cell-specific marker that distinguishes astrocytes from other glial cells.
GFAP immunoreactivity has been shown in immature oligodendrocytes, epiglottic cartilage, pituicytes, papillary meningiomas, myoepithelial cells of the breast and in non-CNS: Schwann cells, salivary gland neoplasms, enteric glia cells, and metastasizing renal carcinomas.
3 isoforms are produced from alternate splicing.
These isoforms differ in the C-terminal region which is encoded by alternative exons.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile PBS.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in 1.2% sodium acetate, 2mg BSA, 0.2mg sodium azide. Reconstitute with 1ml PBS.
Specificity：Recognizes human Glial Fibrillary Acidic Protein. Species Crossreactivity: Rat. Predicted length of 432 residues and MW of 50kD.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Rt
Immunogen：Synthetic peptide corresponding to aa341-356, EMARHLQEYQDLLNVK, from human Glial Fibrillary Acidic Protein, coupled to carrier protein BSA. Species Sequence Homology: Mouse
