Nudel, otherwise known as mitosin-associated protein 1, is a thiol-activated peptidase and member of the nuDE family, highly expressed in the brain, which interacts directly with dynein motors and Lis1, and plays an important role in cortical development and neuron migration.
Nudel is essential during the organization of the cellular microtubule array, and is involved in several dynein- and microtubule-dependent processes such as the centripetal motion of secretory vesicles, coupling of the nucleus and centrosome, and maintaining Golgi integrity.
This product detects a band of ~38kD-39kD in human cerebellum cell lysates.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:38,000Western Blot: 0.1-0.3ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in TBS, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes human Nudel.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide, CRNFAKDQASRKSY, corresponding to internal region of Nudel. Species sequence homology: Mouse, rat
